Potential Side Effects and Safety Considerations The most commonly reported side effects are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, typically mild to moderate and most prominent during dose escalation
[1] [2] Spicy and heavily seasoned foods may irritate the digestive system for some individuals, particularly when gastric emptying is delayed
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Interestingly, a study looking at NAD+ supplementation in humans showed that it had positive effects on body composition, but changes in weight were not seen